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Abstract #10145 Published in IGR 6-1
Corneal neovascularization possibly associated with latanoprost therapy
Orhan M; Kerimoglu H; Irkec MEuropean Journal of Ophthalmology 2003; 13: 88-90
PURPOSE: To report a case of corneal neovascularization possibly associated with latanoprost therapy. METHODS: Case report: A 67-year-old male developed progressive stromal corneal neovascularization in his right eye within eight months of corneal trauma. On admission, he was receiving latanoprost 0.005% therapy. His topical medication was altered: latanoprost was replaced by carteolol hydrochloride 1% twice daily bilaterally and prednisolone acetate 1% was added twice daily in the right eye. RESULTS: One month later, the patient presented with regression of the corneal neovascularization and an increase in visual acuity. CONCLUSIONS: Latanoprost, an arachidonic acid derivative, could have directly or indirectly stimulated corneal neovascularization in this patient with a history of nonpenetrating corneal trauma.
Dr. M. Orhan, Department of Ophthalmology, Hacettepe University School of Medicine, Ankara, Turkey. morhan@hacettepe.edu.tr
Classification:
11.4 Prostaglandins (Part of: 11 Medical treatment)