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Abstract #10203 Published in IGR 6-1
Effects of viscoelastic material on the corneal endothelial cells in trabeculectomy with adjunctive mitomycin C
Shin DB; Lee SB; Kim CSKorean Journal of Ophthalmology 2003; 17: 83-90
The authors evaluated the change in corneal endothelium after trabeculectomy with mitomycin C soaking (0.2 mg/ml, 2.4 ± 1.2 minutes) and the effect of viscoelastic material in reducing this change. In randomly selected cases, 0.05 ml of sodium hyaluronate (Healon) was injected into the anterior chamber (Healon group, n = 20), and the same amount of balanced salt solution was injected into the other eyes (control group, n = 18) at the start of surgery. There were no differences in clinical variables and specular microscopy results between the two groups before surgery. After surgery, the change in endothelial cells was significantly reduced in the Healon group (cell density; -2.5 ± 1.6%, variability of cell area; 5.8 ± 2.5%, and percentage of hexagonal cell; -2.2 ± 0.7%) compared to the control group (-7.7 ± 6.0%, 8.9 ± 4.4%, and -4.8 ± 3.5%, respectively, p < 0.01). In trabeculectomy with mitomycin C, damage to the corneal endothelium was significantly reduced by injecting the viscoelastic material and no significant complications were seen.
Dr. D.B. Shin, Department of Ophthalmology, College of Medicine, Chungnam National University, Daejon, Korea
Classification:
12.8.10 Woundhealing antifibrosis (Part of: 12 Surgical treatment > 12.8 Filtering surgery)
