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Abstract #10348 Published in IGR 6-1
Effects of hypertension and antihypertensive treatment on retrobulbar circulation detected on Doppler sonography
Karadeniz-Bilgili MY; Ekmekci Y; Koksal A; Akarsu C; Ziraman IJournal of Ultrasound in Medicine 2004; 23: 13-17
OBJECTIVE: To study the effect of antihypertensive drugs in essential hypertension and in the central retinal, posterior ciliary, and ophthalmic arteries using Doppler sonography. METHODS: Thirty patients with essential hypertension and 32 control subjects were enrolled in the study. The pulsatility and resistive indices were evaluated in the central retinal, posterior ciliary, and ophthalmic arteries before and two months after treatment with antihypertensive drugs, as well as in the control group. The pulsatility and resistive index values for each artery in each group were compared statistically. RESULTS: There were significant differences in the retrobulbar pulsatility and resistive index values in each artery between the patients with initially diagnosed hypertension and the control group (P < 0.05). There were significant reductions in the resistive and pulsatility index values of the posterior ciliary and ophthalmic arteries after treatment (P < 0.05). For the ophthalmic artery, posttreatment pulsatility and resistive index values did not reach the level of flow measured in the control subjects. CONCLUSIONS: The alteration of Doppler parameters of medication-free patients with hypertension may result from a peripheral vasospasm in the retrobulbar circulation, and the improvement in the Doppler parameters with oral antihypertensive drugs may indicate the importance of early diagnosis in ameliorating hypertension-induced retrobulbar circulation changes.
Dr. M.Y. Karadeniz-Bilgili, Sevil Sokak 16/3, 06590 Cebeci, Ankara, Turkey
Classification:
6.11 Bloodflow measurements (Part of: 6 Clinical examination methods)
9.4.15 Glaucoma in relation to systemic disease (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders)
