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Abstract #10429 Published in IGR 6-1
Intraocular pressure profile of a child on a systemic corticosteroid
Tham CC; Ng JS; Li RT; Chik KW; Lam DSAmerican Journal of Ophthalmology 2004; 137: 198-201
PURPOSE: To report the ocular hypertensive response to high-dose systemic corticosteroid in a pediatric patient. DESIGN: Observational case report. METHODS: A nine-year-old patient with leukemia received oral prednisolone at a dosage of 2.3 mg/kg/d for five weeks, followed by a four-month break and then a four-week course of oral dexamethasone at 10 mg/d. Detailed ocular examination was performed for both eyes before and regularly throughout the two courses of treatment. RESULTS: The intraocular pressure (IOP) in both eyes rose to almost 40 mmHg after only eight days of oral corticosteroid. On stopping systemic corticosteroid, IOP rapidly returned to baseline level within two days. A similar IOP profile was recorded for both eyes during the course of oral dexamethasone. The patient remained largely asymptomatic throughout. CONCLUSIONS: Systemic corticosteroid may give rise to significant but asymptomatic ocular hypertension in pediatric patients.
Dr. C.C. Tham, Department of Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, China. clemtham@hkstar.com
Classification:
9.4.1 Steroid-induced glaucoma (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders)
