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Abstract #104532 Published in IGR 23-2
Prevalence of primary angle-closure disease in retinitis pigmentosa
Pradhan ZS; Shroff S; Bansod A; Poornachandra B; Shetty A; Devi S; Rao DAS; Puttaiah NK; Rao HLIndian Journal of Ophthalmology 2022; 70: 2449-2451
PURPOSE: To determine the prevalence of primary angle-closure disease (PACD) in patients with retinitis pigmentosa (RP). METHODS: This was a retrospective review of the electronic medical records of all RP patients over the age of 10 years attending the Genetics Eye Clinic of a tertiary-care hospital during a 7-year period. Information regarding age, gender, vision, refraction, lens, intraocular pressure (IOP), type of RP, and inheritance pattern using pedigree charts for all patients were obtained. Patients with a shallow anterior chamber, high IOP, or glaucomatous optic discs were referred to the glaucoma department where they underwent additional IOP measurements, a gonioscopy, and disc evaluation by a glaucoma specialist. The prevalence of PACD was determined. RESULTS: A total of 618 RP patients were examined during the study period, of which 95.1% had typical RP. The prevalence of primary angle-closure suspects was 2.9%, primary angle closure was 0.65%, and primary angle-closure glaucoma (PACG) was 2.27%. In contrast, the prevalence of primary open-angle glaucoma was 1.29%. The prevalence of PACG in those older than 40 years was 3.8% (95% confidence interval: 1.6-6.0). CONCLUSION: The prevalence of PACG in RP patients over 40 years was higher than that found in the general population of a similar age (3.8% vs. 0.8%). In our cohort of RP patients, 5.9% had PACD. Hence, gonioscopy is warranted in all RP patients to identify this condition and treat it appropriately.
Department of Glaucoma, Narayana Nethralaya, Bengaluru, Karnataka, India.
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