advertisement
Abstract #104834 Published in IGR 23-2
Topical glaucoma medications - Clinical implications for the ocular surface
Fineide F; Lagali N; Adil MY; Arita R; Kolko M; Vehof J; Utheim TPOcular Surface 2022; 26: 19-49
Glaucoma is a leading cause of irreversible blindness. The use of topical eye drops to reduce intraocular pressure remains the mainstay treatment. These eye drops frequently contain preservatives designed to ensure sterility of the compound. A growing number of clinical and experimental studies report the detrimental effects of not only these preservatives but also the active pharmaceutical compounds on the ocular surface, with resultant tear film instability and dry eye disease. Herein, we critically appraise the published literature exploring the effects of preservatives and pharmaceutical compounds on the ocular surface.
Department of Medical Biochemistry, Oslo University Hospital, Norway; The Norwegian Dry Eye Clinic, Ole Vigs gate 32 E, 0366, Oslo, Norway; Department of Computer Science, Oslo Metropolitan University, Norway; SimulaMet, Oslo, Norway. Electronic address: fre_fin@hotmail.com.
Full article