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Abstract #104928 Published in IGR 23-2
Rhegmatogenous Retinal Detachment Following Initiation of Pilocarpine Hydrochloride Ophthalmic Solution 1.25% for Treatment of Presbyopia
Eton EA; Zhao PY; Johnson MW; Rao RC; Huvard MJRetinal cases & brief reports 2022; 0:
BACKGROUND/PURPOSE: Retinal detachment has previously been reported in association with topical miotic use for treatment of glaucoma. Pilocarpine hydrochloride 1.25% was recently FDA approved for treatment of presbyopia, with no reports of associated retinal detachments in the clinical trial data. METHODS: Case report. RESULTS: We describe two novel cases of unilateral retinal detachment occurring within 10 days of initiation of pilocarpine 1.25% for treatment of presbyopia. The patients were pseudophakic men in their 60s or 70s with pre-existing retinal detachment risk factors such as high myopia, lattice degeneration, and prior retinal detachment. Both affected eyes were treated with pars plana vitrectomy and gas endotamponade with an uncomplicated post-operative course. CONCLUSION: Retinal detachment may be associated with pilocarpine 1.25% use. Caution should be used when considering prescribing this medication in patients with pre-existing retinal pathology.
Department of Ophthalmology and Visual Sciences, University of Michigan Kellogg Eye Center, Ann Arbor, MI.
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