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Abstract #104958 Published in IGR 23-2
Outcomes of Kahook Dual Blade Goniotomy for Uveitis Associated Open Angle Glaucoma or Ocular Hypertension
Miller VJ; Patnaik JL; Young CEC; Soohoo JR; Seibold LK; Kahook MY; Ertel MK; Palestine AG; Pantcheva MBJournal of Glaucoma 2022; 31: 903-908
PRECIS: Kahook Dual Blade goniotomy can successfully lower intraocular pressure in some patients with uveitis-associated ocular hypertension or glaucoma. PURPOSE: The purpose of this study was to report a case series of patients that underwent Kahook Dual Blade goniotomy at a single institution for uveitis-associated ocular hypertension or glaucoma with an open angle. METHODS: We performed a retrospective chart review of all patients with uveitis-associated ocular hypertension or glaucoma who underwent Kahook Dual Blade goniotomy with trabecular meshwork excision alone or in combination with phacoemulsification cataract surgery at a single center between August 2017 and February 2020. The case series included 45 eyes of 37 patients. All eyes developed ocular hypertension refractory to maximum-tolerated medical therapy and required surgical intervention. Two eyes were excluded as they were lost to follow up prior to 5 months post-operatively. Surgical success was defined as reaching the goal intraocular pressure or lower for each patient, including ongoing medical therapy. RESULTS: At most recent follow-up, 25 (55.6%) of 45 eyes had an intraocular pressure that was at goal. Mean follow-up time was 15.2±12.1 months ranging from 0.5 to 36 months post-operatively, considering that patients were eliminated from the data analysis once they required a second surgery. The mean number of pre-operative medications including oral carbonic anhydrase inhibitors was 3.7±1.2 medications. The mean number of post-operative medications through the last clinic visit was 2.5±1.9 medications for a mean reduction of 1.2±1.6 medications (P-value <0.0001*). CONCLUSIONS: This larger case series shows that some patients with uveitis-associated ocular hypertension or glaucoma with an open angle may have success with Kahook Dual Blade goniotomy.
University of Colorado School of Medicine, 1675 Aurora Ct. F731 Aurora, CO 80045.
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