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Abstract #10496 Published in IGR 6-1
Retinal arterial diameters in patients with glaucoma
Remky A; Plange N; Klok J; Arend OSpektrum der Augenheilkunde 2004; 18: 25-30
BACKGROUND: Changes in retinal vessels are reported in patients with severe glaucomatous damage. In this study the authors investigated retinal vessel diameters in 129 eyes with different stages of glaucoma and correlated these with morphological and perimetric data. METHODS: Disc-centered slides of 57 eyes with ocular hypertension (OH), 39 with primary open angle glaucoma (POAG), 28 with normal tension glaucoma (NTG), and seven with secondary glaucoma (secG) were digitized by a high resolution scanning device. Gray scale profiles were performed at one disc diameter distance from the disk perpendicular through the vessels. Measurements were performed at the half-height of the profile. RESULTS: Vessel diameters were significantly correlated with age (arteries: r = -0.32, p = 0.0002; veins: r = -0.40, p = 0.0001) and cup/disc-ratio (r = -0.32, p = 0.004). There was no correlation with the global indices of automated perimetry (Humphrey field analyzer 24-2, full threshold). The group with NTG had significant lower arterial diameters (79 ± 16 μm) than each of the other patients groups which didn't differ from each other (OH: 91 ± 15 μm, POWG: 88 ± 14 μm, secG: 92 ± 18 μm). CONCLUSIONS: Arterial retinal diameters are not correlated with functional data. The decrease in arterial diameter in NTG may indicate the pronounced role of vascular factors in the pathogenesis of this particular entity. LA: German
Dr. A. Remky, Augenklinik des Universitatsklinikums, R.-Westfalis. Tech. Hochsch. Aachen, D-52057 Aachen, Germany
Classification:
9.2.2 Other risk factors for glaucoma (Part of: 9 Clinical forms of glaucomas > 9.2 Primary open angle glaucomas)