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Abstract #105030 Published in IGR 23-2
Iodine-125 plaque brachytherapy for diffuse choroidal hemangioma
Azarcon CP; Azarcon CP; Qiu RLJ; Sobol EK; Hubbard GB; Craven CM; Bergstrom CS; Wells JRRetinal cases & brief reports 2022; 0:
PURPOSE: To report 6 cases of diffuse choroidal hemangioma (DCH) in children treated with iodine-125 plaque brachytherapy at a single tertiary care center. METHODS: Retrospective case series. RESULTS: Six pediatric patients diagnosed with DCH were included in the study. Pre-plaque visual acuity (VA) ranged from 20/150 to no light perception (NLP). All patients had extensive serous retinal detachment at presentation. An iodine-125 radioactive plaque was placed on the affected eye to administer a dose of 34.2-42.1 Gy to the tumor apex over a median of 4 days. Tumor regression and subretinal fluid resolution were observed in all eyes within 17 months of treatment. Visual acuity improved in 2 patients. Radiation-induced cataract and subretinal fibrosis were documented in 1 case, and 1 patient developed radiation retinopathy. No patients developed neovascular glaucoma within a follow-up range of 12-65 months. CONCLUSION: Iodine-125 plaque radiotherapy is an effective option for DCH, although there is a risk for radiation-induced complications.
Department of Ophthalmology, Emory University School of Medicine, Atlanta, GA, USA.
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