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OBJECTIVE: To investigate the protective effect of medicine treatment for reducing intraocular pressure (IOP) on normal-tension glaucoma (NTG). METHODS: Fourty-one eyes of 24 cases with normal tension glaucoma were divided into control group and treated group, which took 0.5% timolol throughout the follow-up period. The follow-up period was 35 - 49 months. Visual field was tested using C-30-2 program of Humprey-630 analyzer, and the detection results and IOP were recorded and analyzed. RESULTS: IOP in the treated group was significantly reduced than that in control group (P < 0.05). The medium defects (MD) of visual field became deeper with significantly differences between two group (P < 0.01). Rate of new defect appearance in control group was significantly higher than that in treated group. A definitely relationship between MD and IOP was also found (r = 0. 92, P < 0. 01). CONCLUSIONS: (1) IOP shows a positive correlation to visual field changes, and reduction of IOP allows to slow down the deterioration of visual acuity in NTG. (2) There exist still some other affecting factors to progression of disease except for IOP. LA: Chinese
W. Dai, Department of Ophthalmology, Xuanwu Hospital, Cap. Univ. of the Medical Sciences, Beijing 100053
9.2.4 Normal pressure glaucoma (Part of: 9 Clinical forms of glaucomas > 9.2 Primary open angle glaucomas)