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Abstract #106825 Published in IGR 23-3
Ciliary Body Schwannoma: A Case Report and Literature Review
El Mokh H; Ben Yahia N; Bouziri M; Gattoufi W; Khabir AJournal of ophthalmic & vision research 2022; 17: 581-586
PURPOSE: To present a case of intraocular schwannoma arising from the ciliary body with description of histological and immunophenotypic characteristics. CASE REPORT: A 32-year-old woman who was followed for glaucoma of the left eye and chronic renal failure at the stage of hemodialysis presented with buphthalmos and two weeks of blurry vision of the left eye. A magnetic resonance imaging exam was performed suspecting melanoma. Enucleation was rapidly performed. The histological examination after HE (Hematoxylin and Eiosin) and HEA50 (Hematoxylin and polychromatic solution EA 50) staining showed proliferation of mesenchymal monomorphic fusiform cells with eosinophilic cytoplasm and small oval nuclei which showed a tendency toward palisading. Some parts of the tumor were hypercellular with a fascicular arrangement (Antoni A pattern); other parts were weakly cellular with a myxoid arrangement (Antoni B pattern). Several Verocay bodies and a lot of hemorrhagic suffusions were described. Mitotic figures were very rare. Immunohistochemistry staining showed that tumor cells were positive for PS100 and vimentin. CONCLUSION: Although ciliary body schwannoma is extremely rare, it should be considered in the differential diagnosis of intraocular tumors.
Department of Pathology, Habib Bourguiba University Hospital, Medenine, Tunisia.
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