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Abstract #107859 Published in IGR 23-4
Selective laser trabeculoplasty as adjunctive treatment for open-angle glaucoma following incisional glaucoma surgery in Chinese eyes
Zhu J; Guo JWorld journal of clinical cases 2023; 11: 780-787
BACKGROUND: Selective laser trabeculoplasty (SLT) is a relatively safe and effective therapy in lowering intraocular pressures (IOP) for glaucoma. AIM: To study the long-term effects of SLT on IOP and number of glaucoma medications used in Chinese eyes. METHODS: This is a retrospective study in which 75 eyes of 70 patients with open-angle glaucoma (OAG, =36) and eyes with prior glaucoma surgery (PGS, =39) were included. Changes in mean IOP and number of glaucoma medications used evaluated at 1 d, 1 wk, 1 mo, 3 mo, 6 mo, 12 mo, and 36 mo after laser treatment. RESULTS: All patients (33 male, 37 female) were Chinese. The mean age was 44.34 ± 16.14 years. Mean pre-SLT IOP was 22.75 ± 2.08 mmHg in OAG and 22.52 ± 2.62 mmHg in PGS. Mean IOP was significantly reduced 1 d, 1 wk, 1 mo and 3 mo after laser treatment ( < 0.05, respectively). Whereas, there were no significant differences between baseline and SLT treated groups at the 6 month both in OAG ( = 0.347, > 0.05) and in PGS ( = 0.309, > 0.05). Six months after SLT treatment, some patients received retreatment of SLT or were given more topical IOP-lowering medication to control the IOP. By the end of our study, the average IOP decreased to 20.73 ± 1.82 mmHg in OAG and 20.49 ± 1.53 mmHg in PGS groups. The number of glaucoma medications used was significantly reduced until the end of 3 years compared to baseline. CONCLUSION: SLT could reduce IOP as adjunctive treatment both in OAG and PGS groups. SLT significantly reduced the number of glaucoma medications used 3-years following treatment in glaucoma patients.
Department of Ophthalmology, The Third People's Hospital of Chengdu, Affiliated Hospital of Southwest Jiao Tong University, Affiliated Chengdu Second Clinical College of Chongqing Medical University, Chengdu 610031, Sichuan Province, China.
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