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Abstract #108058 Published in IGR 23-4
Clinical Features, Long-Term Outcomes, and Prognostic Factors of Eales' Disease in Korean Patients
Lee SM; Jung JH; Lee J; Choi EY; Shin JY; Kim MOcular Immunology and Inflammation 2023; 0: 1-7
PURPOSE: We studied Korean patients with Eales' disease to document clinical features, long-term outcomes, and explore its association with TB, given South Korea's high TB burden. METHODS: We retrospectively reviewed medical records of Eales' disease patients for clinical characteristics, long-term outcomes, and its association with TB. RESULTS: Among 106 eyes, the average age of diagnosis was 39.28 years, with 82.7% male and 58.7% having unilateral involvement. Patients who underwent vitrectomy showed greater long-term improvement in visual acuity ( = .047), while those with glaucoma filtration surgery showed less improvement ( = .008). Having glaucoma through disease progression was associated with poor visual outcomes (odds ratio=15.556, < .02). 27 out of 39 patients (69.23%) who underwent IGRA screening tested positive for TB. CONCLUSIONS: In Korean patients with Eales' disease, we observed male predominance, unilateral presentation, older age of onset, and a link with TB. Timely diagnosis and management should be considered to maintain good vision in patients with Eales' disease.
Department of Ophthalmology, Institute of Vision Research, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.
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