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Abstract #108640 Published in IGR 23-4
Unilateral chronic angle-closure glaucoma in a pediatric patient with neurofibromatosis: a case report
Jiang M; Zhang J; Wan X; Ding Y; Xie FJournal of International Medical Research 2023; 51: 3000605231173828
Neurofibromatosis type 1 (NF1) is an autosomal dominant genetic disease that causes multi-system damage. It is rarely associated with angle-closure glaucoma, especially in pediatric patients. We herein report a case of unilateral chronic angle-closure glaucoma in a patient with NF1. A 5-year-old girl with a large subcutaneous soft mass and multiple scattered coffee-milk spots presented with low vision, increased intraocular pressure, and angle closure in her right eye. Lisch nodules were seen in both eyes. In her right eye, ectropion uveae was observed at the top and bottom margins of the pupil. Magnetic resonance imaging of the skull and orbit revealed no abnormalities. Finally, trabeculectomy was performed on the right eye, after which the right eye showed a stable intraocular pressure. NF1 combined with angle-closure glaucoma is rare and easily missed in the clinical setting. Early diagnosis and treatment may achieve good results.
Eye Institute of Shandong First Medical University, Qingdao Eye Hospital of Shandong First Medical University; State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology; School of Ophthalmology, Shandong First Medical University.
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