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Abstract #10872 Published in IGR 6-2
Prevalence of pseudoexfoliation syndrome in Ethiopian patients scheduled for cataract surgery
Teshome T; Regassa KActa Ophthalmologica Scandinavica 2004; 82: 254-8
PURPOSE: To evaluate the prevalence of pseudoexfoliation syndrome (PEX) among Ethiopian patients with age-related cataract scheduled for surgery. PATIENTS AND METHODS: In a prospective study, 229 consecutive eyes with age-related cataract scheduled for surgery were evaluated for the prevalence of PEX, type of cataract, intraocular pressure (IOP) and glaucoma. RESULTS: The mean age of the 229 patients was 62.1 ± 10.5 years (range 47-91 years). The prevalence of PEX was 39.3% (90 of 229 eyes). Pseudoexfoliation syndrome was bilateral in 62.2% (56/90) of cases. The mean age of those with PEX (63.7 ± 10.7 years) was significantly more than that of those without PEX (60.3 ± 9.2 years) (p = 0.01). The prevalence of PEX significantly increased with age (p = 0.02). Patients with hypermature cataract had significantly more PEX (p < 0.001). Mean IOP was significantly higher in eyes with PEX (18.4 ± 3.2 mmHg) than in those without PEX (15.8 ± 3.6 mmHg) (p < 0.001). Significantly more eyes in the PEX group had IOP > 21 mmHg (p < 0.01) and established glaucoma (p < 0.05). An incidence of PEX was found in all major ethnic groups in Ethiopia. There was no significant difference in the prevalence of PEX between the different ethnic groups (p > 0.5). CONCLUSIONS: The prevalence of PEX among Ethiopian patients with cataract is high and occurs at a relatively younger age when compared to previous reports from Europe. Pseudoexfoliation syndrome has been found to be significantly associated with hypermature cataract, higher mean IOP, IOP > 21 mmHg and glaucoma. Population-based studies are recommended to evaluate the prevalence of PEX in the general population and its association with cataract and glaucoma.
Department of Ophthalmology, Faculty of Medicine, Addis Ababa University, Ethiopia. tiliksew@yahoo.com
Classification:
9.4.4.1 Exfoliation syndrome (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders > 9.4.4 Glaucomas associated with disorders of the lens)
