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Abstract #109224 Published in IGR 24-1
Interface fluid syndrome after LASIK surgery: retrospective pooled analysis and systematic review
Ravipati A; Pradeep T; Donaldson KEJournal of Cataract and Refractive Surgery 2023; 49: 885-889
Interface fluid syndrome (IFS) is a complication associated with laser in situ keratomileusis (LASIK) surgery where a fluid pocket in the corneal stroma decreases visual acuity. A systematic review of IFS cases using PRISMA guidelines was performed yielding a total of 33 patients. 2 outcomes were selected for logistic regression analysis: final corrected distance visual acuity (CDVA) and need for surgical management. RESULTS: showed 33.3% of patients required surgery, 51.5% had their IFS resolve within 1 month or sooner, and 51.5% had final CDVA 20/25 or better. Higher presenting intraocular pressure (IOP) and duration of IFS ≤1 month was associated with higher odds of final CDVA 20/25 or better (adjusted odds ratio [aOR] 1.12, P = .04; aOR 7.71, P = .02, respectively). Endothelial cell dysfunction led to 17.55 greater odds for requiring surgical compared to medical management (aOR 0.36, P = .04). Presenting IOP and duration of IFS predicted final CDVA, while prior endothelial cell dysfunction predicted need for surgery.
From the Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida (Ravipati, Donaldson); Scheie Eye Institute, University of Pennsylvania, Philadelphia, Pennsylvania (Pradeep).
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