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OBJECTIVE: To determine normal central and paracentral corneal thickness measurements in the pediatric population and to determine if these measurements are consistent across different pediatric age groups and different racial groups. DESIGN: Prospective observational case series. METHODS: Pachymetry measurements were performed on 198 eyes of 108 children. The measurements were taken centrally as well as at four paracentral sites 3 mm from the corneal center at the 3, 6, 9, and 12 o'clock positions. The two-tailed t test was used for comparison of the continuous means for values of corneal thickness. Analysis of variance (ANOVA) was performed to determine differences among age and ethnic groups RESULTS: The mean central corneal thickness (CCT) was 549 ± 46 μm. Paracentral corneal thickness mean values, as measured 3 mm from the corneal center, were as follows: superior, 575 ± 52 μm; nasal, 568 ± 50 μm; inferior, 568 ± 51 μm; and temporal, 574 ± 47 μm. The mean CCT values were significantly thinner than at each of the mean paracentral points (P < .05 for each comparison, paired t test). Paracentral corneal thickness measurements demonstrated no significant differences between locations (P > .05, variance analysis). The mean CCT ± SD for each age group was as follows: 6 to 23 months, 538 ± 40 μm; 2 to 4 years, 546 ± 41 μm; 5 to 9 years, 566 ± 48 μm; and 10 to 18 years, 554 ± 35 μm (ANOVA P = .012). ANOVA performed on central pachymetry values demonstrated no significant differences among racial subgroups. CONCLUSIONS: Pediatric central and paracentral corneal thicknesses increase slowly over time and reach adult thicknesses at 5 to 9 years of age.
Dr. M.A. Hussein, Cullen Eye Institute, Baylor College of Medicine, Department of Ophthalmology, Texas Children's Hospital, Houston, TX, USA
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