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Abstract #113216 Published in IGR 24-3
Chen ZQ; Chen W; Deng CH; Guo JM; Zhang H; Wang JMInternational Journal of Ophthalmology 2023; 16: 1482-1488
See also comment(s) by Alex Huang & Seung Hyen Lee •
AIM: To investigate the aqueous vein by using enhanced depth imaging optical coherence tomography (EDI-OCT) and optical coherence tomography angiography (OCTA). METHODS: In this cross-sectional comparative study, 30 healthy participants were enrolled. Images of the aqueous and conjunctival veins were captured by EDI-OCT and OCTA before and after water loading. The area, height, width, location depth and blood flow of the aqueous vein and conjunctival vein were measured by Image J software. RESULTS: In the static state, the area of the aqueous vein was 8166.7±3272.7 µm, which was smaller than that of the conjunctival vein (13 690±7457 µm,<0.001). The mean blood flow density of the aqueous vein was 35.3%±12.6%, which was significantly less than that of the conjunctival vein (51.5%±10.6%,<0.001). After water loading, the area of the aqueous vein decreased significantly from 8725.8±779.4 µm (baseline) to 7005.2±566.2 µm at 45min but rose to 7863.0±703.2 µm at 60min (=0.032). The blood flow density of the aqueous vein decreased significantly from 41.2%±4.5% (baseline) to 35.4%±3.2% at 30min but returned to 45.6%±3.6% at 60min (=0.021). CONCLUSION: The structure and blood flow density of the aqueous vein can be effectively evaluated by OCT and OCTA. These may become biological indicators to evaluate aqueous vein changes and aqueous outflow resistance under different interventions in glaucoma patients.
Department of Ophthalmology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei Province, China.
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