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OBJECTIVE: To determine the characteristic of intraocular pressure (IOP) distribution and its association with other factors such as ages, myopia, diabetic retinopathy, nuclear cataract and glaucoma in populations of rural and urban communities of Beijing. METHODS: The 4451 residents aged 40 or over were clustered sampled. Clinical ocular examinations were curried out according to a standard protocol, and one eye of each subject was selected for data analysis. RESULTS: The mean IOP of rural subjects was not significantly different from that of urban subjects. The mean IOP of aged > 70 subjects was significantly lower than that aged < 70 subjects in 4429 subjects (P < 0.05). In normal population, IOP distribution was a Gaussian-like curve slightly skewed to the right (skewness = 0.271) with the mean value (15.90 ± 2.82) mmHg (95% CI 10.37-21.43 mmHg). The IOP levels of subjects with myopia, diabetic retinopathy and glaucoma were significantly higher (all P < 0.05). The difference of IOP between the subjects with and without cataract surgery history was statistically insignificant. Age and nuclear cataract were partly negatively associated with IOP. Myopia, diabetic retinopathy and glaucoma were partly positively associated with IOP (all P < 0.05). CONCLUSION: The normal IOP range with non-contact tonometry in general population is near to that with Goldmann applanation tonometry with the value about 10-21 mmHg. IOP is decreased with the increase of age after 70 years. The IOP of the subjects that received prior cataract surgery is not lower than ones without cataract surgery. LA: Chinese
Dr. J. Li, Beijing Institute of Ophthalmology, Affiliated Tongren Eye Center, Cap. University of Medical Science, Beijing 100730, China
1.1 Epidemiology (Part of: 1 General aspects)