advertisement
Abstract #11517 Published in IGR 6-3
Detection level of glaucoma and ocular hypertension in Wroclaw population - Wroclaw Epidemiological Study
Nizankowska MH; Kaczmarek R; Jakubaszko JAdvances in Clinical and Experimental Medicine 2004; 13: 607-613
OBJECTIVES: The aim of the study was to determine the prevalence of glaucoma as well as the glaucoma detection level in the population of Wroclaw based on the results of Wroclaw Epidemiological Study of Glaucoma. The second aim was to assess the prevalence of ocular hypertension (OH) in this population as a moderate or serious risk factor for glaucoma. MATERIAL AND METHODS: The study was carried out in the representative sample of 4843 subjects aged from 40 to 79, recruited out of the PESEL database by proportional simple random sampling selection with stratification in 10 years age intervals. The algorithm of selection was prepared by Main Department of Statistics. After the first stage of the study which included 5 screening tests and medical history, 1314 subjects suspected of glaucoma were found, which entered the second stage of the study and underwent full ophthalmological examination aimed at glaucoma diagnosis. The second stage made possible the diagnosis of glaucoma as well as determining its type, or in the contrary exclusion of the disease. Some patients were subject to follow up after 3, 6 and 12 months. The results of those observations enabled authors to make a final diagnosis. RESULTS: The prevalence of glaucoma in Wroclaw population aged 40-79 was 1.6%. The detection level of glaucoma in examined population was 29%. Various forms of open angle-glaucoma (OAG) accounted for 91% of detected cases. Ocular hypertension (OH) was detected in 1.9% of the population. The pachymetric measurement of central corneal thickness (CCT) of eyes with OH revealed, that in 26% of eyes CCT value was from 555 to 588 μm, and those subjects are in the risk group which requires monitoring. In 12.5% of eyes CCT value was under 555 μm and here the risk of glaucoma is even higher, which can already justify the preventive treatment. CONCLUSIONS: The study revealed low glaucoma detection level in Wroclaw population - only 29% - and low sensitivity (53%) of tonometry as the screening method. Best correlation between sensitivity and specificity of the screening examination (73% and 92%, respectively) was found for the ophthalmoscopic assessment of ocular nerve head. The evaluation of CCT can be of value for the assessment of the risk for glaucoma development in patients with OH. LA: Polish
Dr. M.H. Nizankowska, Katedra i Klinika Okulistyki, AM, ul. Chalubinnskiego 2a, 50-368 Wroclaw, Poland
Classification:
1.1 Epidemiology (Part of: 1 General aspects)
