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Abstract #11529 Published in IGR 6-3
Abnormal visual evoked potentials as a sign of lesions in the optic tract in patients with obstructive sleep apnoea syndrome
Misiuk Hojlo M; Brzecka A; Ejma M; Kobierzycka AAdvances in Clinical and Experimental Medicine 2004; 13: 561-565
BACKGROUND: Obstructive sleep apnoea (OSA) syndrome with repetitive nocturnal sleep hypoxemia may be considered as a risk factor of optic nerve damage. Objectives. The aim of the study was to detect the lesions in optic tract that might occur in the patients with severe OSA syndrome. MATERIAL AND METHODS: In 16 men with severe OSA syndrome (apnoea index > 35, mean 60 ± 12) the detailed ophthalmologic studies, including automatic perimetry, and the studies of the latency and amplitude of visual evoked potentials (VEPs) have been performed. RESULTS: In patients with severe OSA syndrome the mean latency of VEPs was 119 ± 7.6 ms. In 81% of patients the latency of VEPs was prolonged and exceeded 118 ms. In four patients the deficits in visual field have been found and in three of them there was prolongation of the latencies of VEPs. In patients with perimetric abnormalities there were extremely severe respiratory disturbances during sleep: mean apnoea index was 67 ± 5, mean SaO2 at the end of the apnoeas was 79 ± 5% (Adv Clin Exp Med 2004, 13, 561-565). CONCLUSIONS: Abnormal VEPs might be an early marker of optic tract lesions in OSA patients.
Dr. M. Misiuk-Hojlo, Department of Eye Diseases, Wroclaw Medical University, T. Chalubinskiego 2, 50-367 Wroclaw, Poland
Classification:
6.7 Electro-ophthalmodiagnosis (Part of: 6 Clinical examination methods)
10 Differential diagnosis e.g. anterior and posterior ischemic optic neuropathy
