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Abstract #11530 Published in IGR 6-3
Combined application of visual electroretinography and perimetry in the early primary open angle glaucoma
Shi Y; Chang B; Chen J; Guo J; Yi EChinese Ophthalmic Research 2004; 22: 424-427
OBJECTIVE: To evaluate the clinical value of different electroretinographies and automated perimetry in the diagnosis of early primary open angle glaucoma (POAG). METHODS: Ten normal individuals (20 eyes) and 10 patients (20 eyes) with early POAG were examined by flash electroretinography (F-ERG), pattern electroretinography (P-ERG) and pattern visual evoked potential (P-VEP). Five normal individuals and 5 patients (10 eyes) in the two groups were examined by the multifocal electroretinography (mERG). Eight normal individuals (16 eyes) and 10 patients (20 eyes) in the two groups were tested by blue-on-yellow (B/Y) and white-on-white (W/W) automated perimetries. The testing results between two groups were analyzed. RESULT: The changes of P-ERG, P-VEP, mERG, B/Y and W/W were found in the early POAG group. The N95, latency of P-ERG was (96.85 ± 13.93) ms in POAG group and (89.83 ± 11.31) ms in the control group. The P-VEP showed reduction of amplitude and prolong of latency of P100 wave, but no significant difference compared to the control group. The amplitudes of secondary order response of mERG were significantly declined, especially at the 4th - 6th rings. The abnormal visual field change was observed by B/Y pemeritry (mean sensitivity 20.23 ± 4.04), showing more sensitive than W/W pemeritry (mean sensitivity 25.57 ± 3.45). CONCLUSION: B/Y visual field examination combined with different electroretinographies is more sensitive to the early diagnosis of POAG. B/Y perimetry and P-ERG are the optimal selections of the early cases without cup/disc ratio changes. LA: Chinese
Dr. Y. Shi, Department of Ophthalmology, Xi'an Central Hospital, Xi'an 710003, China
Classification:
6.7 Electro-ophthalmodiagnosis (Part of: 6 Clinical examination methods)
