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Abstract #117640 Published in IGR 24-4
Glucocorticoid-Induced Ocular Hypertension and Glaucoma
Harvey DH; Harvey DH; Sugali CK; Mao WClinical Ophthalmology 2024; 18: 481-505
Glucocorticoid (GC) therapy is indicated in many diseases, including ocular diseases. An important side-effect of GC therapy is GC-induced ocular hypertension (GIOHT), which may cause irreversible blindness known as GC-induced glaucoma (GIG). Here, we reviewed the pathological changes that contribute to GIOHT including in the trabecular meshwork and Schlemm's canal at cellular and molecular levels. We also discussed the clinical aspects of GIOHT/GIG including disease prevalence, risk factors, the type of GCs, the route of GC administration, and management strategies.
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