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Abstract #12092 Published in IGR 7-1

Nonarteritic ischemic optic neuropathy developing soon after use of sildenafil (viagra): a report of seven new cases

Pomeranz HD; Bhavsar AR
Journal of Neuro-Ophthalmology 2005; 25: 9-13


Seven patients, aged between 50 and 69 years, had typical features of nonarteritic anterior ischemic optic neuropathy (NAION) within 36 hours after ingestion of sildenafil citrate (Viagra) for erectile dysfunction. Six patients had vision loss within 24 hours after use of the agent. Final visual acuity in the affected eye ranged from 20/20 to light perception. Both eyes were affected in one individual. All affected individuals had pre-existing hypertension, diabetes, elevated cholesterol, or hyperlipidemia. Seven similar cases have been previously reported. Sildenafil may provoke NAION in individuals with an arteriosclerotic risk profile.

Dr. H.D. Pomeranz, Department of Ophthalmology, University of Minnesota Medical School, Minneapolis, MN 55455, USA. pomer010@umn.edu


Classification:

10 Differential diagnosis e.g. anterior and posterior ischemic optic neuropathy



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