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Abstract #12239 Published in IGR 7-2
Ocular hypertension in case of tubulointerstitial nephritis and uveitis syndrome
Murase H; Mochizuki K; Hori Y; Yamada S; Sawada AJapanese Journal of Clinical Ophthalmology 2005; 59: 353-357
A 15-year-old boy presented with conjunctival hyperemia and pain in his right eye since one week before. The visual acuity was 1.0 in either eye. Intraocular pressure (IOP) was within normal range. Both eyes showed ciliary injection and cells in the anterior chamber. Right optic disc showed hyperemia. Both eyes showed dilated retinal veins. Urinalysis showed elevated N-acetyl-glucosaminidase, α1 and β2 microglobulins, leading to the diagnosis of tubulointerstitial nephritis and uveitis (TINU) syndrome. Systemic prednisolone and topical betamethasone led to improvement. Prednisolone was discontinued 7 months later. Intractable IOP rise occurred 4 months later in spite of absence of iritis. IOP was controlled after withdrawal of topical betamethasone. The patient was duing well 18 months thereafter. Steroid glaucoma is suspected as the cause of observed IOP elevation. LA: Japanese
Dr. H. Murase, Department of Ophthalmology, JA Gifu Koseiren Chuno Gen. Hospital, 5-1 Wakakusadori, Seki 501-3802, Japan
Classification:
9.4.6 Glaucomas associated with inflammation, uveitis (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders)
