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See also comment(s) by Joseph Caprioli •
AIM: To assess the intraocular pressure (IOP) variability in patients with primary open angle glaucoma (POAG) under clinical treatment who reached an established target pressure based on isolated office readings. METHODS: Retrospective analysis of 65 eyes from 65 POAG patients under clinical therapy who submitted to modified diurnal tension curve (mDTC) (measurements at every 3 hours between 8 am and 5 pm) followed by a water drinking test (WDT). All subjects had established target IOP ≤ 15 mmHg at 11 am or 2 pm. IOP variability during mDTC or WDT was evaluated. RESULTS: mDTC revealed IOP measurements ≥ 17 mmHg in 16 of 65 eyes (24.6%). Nine eyes (13.8%) presented values ≥ 18 mmHg. The highest IOP detected by mDTC was 20 mmHg in one patient (1.5%). WDT demonstrated IOP values ≥ 17 mmHg in 32 of 65 eyes (49.2%). 22 eyes (33.8%) presented values ≥ 18 mmHg after water ingestion. Moreover, IOP levels ≥ 20 mmHg were observed in 14 eyes (21.5%). CONCLUSION: A great percentage of POAG patients undergoing clinical treatment and with IOP control based on single office measurement present significantly higher IOP measurements when performing mDTC and, especially, the WDT.
Dr. M. Hatanaka, Glaucoma Department, University of Sao Paulo School of Medicine, Sao Paulo, Brazil, Rua Capote Valente 171 Ap 122, Sao Paulo, SP, Brazil, 05409-000. marcelohatanaka@uol.com.br.
11.1 General management, indication (Part of: 11 Medical treatment)