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Abstract #12515 Published in IGR 7-2

Assessment of nerve fiber layer thickness before and after laser in situ keratomileusis using scanning laser polarimetry with variable corneal compensation

Halkiadakis I; Anglionto L; Ferensowicz M; Triebwasser RW; van Westenbrugge JA; Gimbel HV
Journal of Cataract and Refractive Surgery 2005; 31: 1035-1041


PURPOSE: To determine the effect of laser in situ keratomileusis (LASIK) on retinal nerve fiber layer (RNFL) thickness measurements obtained by scanning laser polarimetry with variable corneal compensation (SLP-VCC). SETTING: Gimbel Eye Centre, Calgary, Alberta. METHODS: Retinal nerve fiber layer thickness measurements were performed in both eyes of 25 consecutive healthy patients the day of LASIK surgery and 1 month after by trained examiners using the GDx-VCC nerve fiber analyzer. Thickness measurements and all other parameters provided by the software of the machine before and after LASIK were analyzed using the paired Student t test. RESULTS: Mean age of the patients was 39 years ± 9.6 (SD) (range 24 to 57 years). The mean preoperative spherical equivalent was -4.15 ± 1.76 diopters (D) (range -1.0 to -7.50 D) and the mean postoperative spherical equivalent, 0.12 ± 0.39 D (range -0.75 to +1.00 D). Mean ablation depth was 62 ± 23 μm. No statistically significant difference was found in SLP parameters after LASIK (P < .05). No clinically significant difference in RNFL thickness measurements was noted in any eye. CONCLUSION: These data suggest that SLP-VCC mean thickness measurements are not influenced by LASIK-induced alterations in corneal architecture. Measurements obtained with SLP-VCC before surgery may be used for future comparisons.

Dr. I. Halkiadakis, Gimbel Eye Centre, Calgary, Alberta T3A 2N1, Canada. ihalkiadakis@yahoo.gr


Classification:

6.9.1 Laser scanning (Part of: 6 Clinical examination methods > 6.9 Computerized image analysis)
8.4 Refractive surgical procedures (Part of: 8 Refractive errors in relation to glaucoma)



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