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A prospective study was made on 25 eyes of 15 cases of normal-tension glaucoma who had been treated by topical medication other than latanoprost. The medication was switched to latanoprost only. All the eyes were evaluated as to intraocular pressure (IOP), visual field and morphology of the optic disc before and one year after treatment with latanoprost. The ages of patients ranged from 42 to 82 years, average 68 years. The IOP averaged 15.1 ± 2.6 mmHg before and 13.4 ± 2.2 mmHg one year after treatment by latanoprost. The difference was significant (p < 0.01). Visual field showed improved mean deviation. No changes had set in regarding parameters of optic disc morphology. The findings show that latanoprost induces hypotensive effect in normal-tension glaucoma and that it stabilizes the visual field and optic disc morphology for at least one year. LA: Japanese
Dr. H. Ogata, Department of Ophthalmology, Kitasato University School of Medicine, 1-15-1 Kitasato, Sagamihara 228-8555, Japan
11.4 Prostaglandins (Part of: 11 Medical treatment)