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Abstract #12645 Published in IGR 7-3
Effect of intraoperative intracameral 2% hydroxypropyl methylcellulose viscoelastic during trabeculectomy
Agarwal HC; Anuradha VK; Titiyal JS; Gupta VOphthalmic Surgery Lasers and Imaging 2005; 36: 280-285
BACKGROUND AND OBJECTIVE: To evaluate the effect of intraoperative intracameral injection of 2% hydroxypropyl methylcellulose (HPMC) on anterior chamber depth and intraocular pressure (IOP) following trabeculectomy in eyes with uncontrolled primary open-angle glaucoma in a prospective randomized manner. PATIENTS AND METHODS: Thirty consecutive eyes with primary open-angle glaucoma scheduled for trabeculectomy were randomized to conventional trabeculectomy without HPMC injection (group I; n = 15) or to intracameral injection of 2% HPMC during trabeculectomy (group II; n = 15). All patients were observed serially on days 1, 3, 5, 7, and 14 and months 1, 3, and 6 postoperatively. The main outcome measure was restoration of anterior chamber depth to preoperative level with IOP of less than 21 mmHg with no additional antiglaucoma medication or surgery. RESULTS: The anterior chamber depth decreased from 2.5 ± 0.53 to 1.5 ± 0.94 mm on postoperative day 1 in group I and increased slightly from 2.4 ± 0.43 to 2.5 ± 0.36 mm on postoperative day 1 in group II (P = .04). Overall, the IOP decreased to 5.0 ± 2.8 mmHg in group I (87% reduction) and 9.0 ± 4.6 mmHg in group II (70% reduction). Two eyes developed postoperative flat anterior chamber and related complications in group I, whereas none of the eyes in group II developed such complications. CONCLUSIONS: Intracameral injection of 2% HPMC during trabeculectomy helps to maintain anterior chamber depth and reduces incidence of complications related to shallow anterior chamber depth following trabeculectomy.
Dr. H.C. Agarwal, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All-India Institute of Medical Sciences, Ansari Nagar, New Delhi, India
Classification:
12.8.1 Without tube implant (Part of: 12 Surgical treatment > 12.8 Filtering surgery)
