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Abstract #12647 Published in IGR 7-3
Mitomycin C and sodium hyaluronate in tabeculectomy
Feng J-H; Song W-L; Zhao C-YInternational Journal of Ophthalmology 2005; 5: 782-784
AIM: To explore the application of mitomycin C (MMC) and sodium hyaluronate (Healon) in trabeculectomy. METHODS: A total of 61 cases (65 eyes) were randomly divided into Treatment Group (31 cases, 34 eyes) and Control Group (30 cases, 31 eyes). MMC and Healon were used in the trabeculectomy in the Treatment Group, but not in that of the Control Group. RESULTS: At 2 weeks after surgery, there were 34 eyes with intraocular pressure (IOL) ≤ 21 mmHg in Treatment Group, while 25 eyes had IOL ≤ 21 mmHg and the other 6 eyes > 21 mmHg. Therefore, there were significant differences between the two groups (P > 0.01). Postoperative shallow anterior chamber appeared in 3 eyes of Treatment Group and 10 eyes of Control Group, respectively, indicating significant differences between the two groups (P < 0.05). Postoperative filtering bleb IX occurred in 1 eye of Treatment Group and 6 eyes of Control Group, respectively, also indicating sharp differences between the two groups (P < 0.05). CONCLUSION: MMC and Healon can markedly reduce the postoperative applications and increase the success rate in trabeculectomy, which is an effective method applied in trabeculectomy. LA: Chinese
Dr. J.-H. Feng, Department of Ophthalmology, Central Hospital of Lijin County, Lijin 257400 Shandong Province, China
Classification:
12.8.10 Woundhealing antifibrosis (Part of: 12 Surgical treatment > 12.8 Filtering surgery)
