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Abstract #12729 Published in IGR 7-3
Clinical significance of photopic negative response in early glaucoma
Li MChinese Ophthalmic Research 2005; 23: 433-436
The photopic negative response (PhNR) from photopic electroretinogram is a slowly negative potential following positive b wave. It can be recorded using white or color flash stimulation under the color light background. When using color stimuli and color background, the PhNR amplitude is obviously increased. Animal experiments determine that PhNR arise from retinal ganglion cells and their axons. Experimental glaucoma can suppress PhNR amplitude even visual sensitivity loss of perimetry is still mild. PhNR amplitudes are selective reduced in some suspicious or primary open angle glaucoma patients. PhNR has a potential role of evaluating visual function in the early detection and monitoring for the progression of glaucomatous damage. LA: Chinese
Dr. M. Li, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, China
Classification:
6.7 Electro-ophthalmodiagnosis (Part of: 6 Clinical examination methods)