advertisement
Abstract #13200 Published in IGR 7-3
The prevalence of pseudoexfoliation syndrome in a Japanese population: the Hisayama study
Miyazaki M; Kubota T; Kubo M; Kiyohara Y; Iida M; Nose Y; Ishibashi TJournal of Glaucoma 2005; 14: 482-484
PURPOSE: To examine the prevalence and systemic associations of pseudoexfoliation syndrome (PXS) in a Japanese population. METHODS: In 1998, a cross-sectional population-based survey was conducted among residents of Hisayama. Of a total of 3054 residents living in Hisayama, Japan, aged 50 years or older, 1844 consented to participate in the study. Each participant underwent a comprehensive examination that included an ophthalmic examination. The presence of any pseudoexfoliation material on the iris or lens capsule was determined by slit-lamp examination. The participants were classified as having pseudoexfoliation syndrome if any pseudoexfoliation material was present in either eye. Using these cross-sectional data, logistic regression analyses were performed to determine the systemic associations of pseudoexfoliation syndrome. The following eight possible correlates were considered: age, sex, hypertension, diabetes, hyperlipidemia, current smoker, alcohol intake, and body mass index. RESULTS: Among the subjects, 50 (3.4%) had pseudoexfoliation syndrome. The prevalence of pseudoexfoliation syndrome increased significantly with age. Multiple logistic regression analysis showed that age and hypertension were significantly associated with pseudoexfoliation syndrome. CONCLUSION: The prevalence of pseudoexfoliation syndrome in a Japanese population was 3.4%, and increased with age. This study suggests that hypertension strongly correlates with pseudoexfoliation syndrome in our population-based sample of Japanese subjects aged 50 years or older.
Dr. M. Miyazaki, Department of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan. miho-m@med.kyushu-u.ac.jp
Classification:
9.4.4.1 Exfoliation syndrome (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders > 9.4.4 Glaucomas associated with disorders of the lens)