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PURPOSE: To investigate the levels of renin-angiotension system (RAS) components in normal tension glaucoma patients and normal controls. METHODS: Blood samples were obtained from 11 normal tension glaucoma (NTG) patients and 11 age and sex matched controls. The levels of renin and angiotensin A II of 11 NTG patients and normal controls were examined by radio-immunity test. Statistical analyses were performed by paired t test. RESULTS:The levels of renin of NTG patients and normal controls are (769.085t 183.217) pg/ml/n and (822.035 ± 124.140) pg/ml/n, while the levels of angiotensin A II of NTG patients and normal controls are (37.347 ± 10.669)pg/ml and (24.836 ± 10.665) pg/ml respectively. No statistically significant differences were observed between the levels of renin and angiotensin among NTG patients and normal controls. CONCLUSION: There were not many abnormalities of the levels of circulating rennin and angiotensin A II of NTG patients in our study.
Dr. H. Yun. Department of Ophthalmology, Peking University Shenzhen Hospital, Shenzhen 518036, China
9.2.4 Normal pressure glaucoma (Part of: 9 Clinical forms of glaucomas > 9.2 Primary open angle glaucomas)