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Abstract #13609 Published in IGR 8-2
The clinical observation of nonperforating trabecular surgery with reticulated hyaluronic acid implant for treatment of open-angle glaucoma
Guo Y; Xia X-B; Jiang H-B; Wang P-B; Huang P-G; Liu S-Z; Xu X-LInternational Journal of Ophthalmology 2006; 6: 92-96
AIM: To evaluate the clinical effect of nonperforating trabecular surgery (NPTS) combined with reticulated hyaluronic acid implant on the treatment of open-angle glaucoma. METHODS: NPTS combined with reticulated hyaluronic acid implant was performed on 48 eyes of 34 patients with open-angle glaucoma. Postoperative visual acuity, intraocular pressure (IOP), bleb appearance, intraocular reactions and complications were observed. RESULTS: The mean follow-up was 8.2 ± 4.14 months. The mean IOP was 7.71 ± 2.69 mmHg postoperatively, significantly higher than the IOP preoperatively 34.18 ± 13.30 mmHg (t = 14.710, P < 0.001). The number of anti-glaucoma drugs was 2.77 ± 0.77 preoperatively, more than the drugs 0.71 ± 1.05 postoperatively (t = 4.616, P < 0.001). On the last visit, in 46 eyes (96%) the IOP was ≤ 21mmHg, among which there were 27 eyes (58.7%) without anti-glaucoma medicine and 19 eyes with anti-glaucoma medicine. There were no flare and cells in the anterior chamber in 24 eyes. In 10 eyes there was only slight flare that disappeared in 2-5 days. In 8 eyes there was a small amount of hyphema that was absorbed in 2-4 days. In 6 eyes there was macular edema with hypotension that was disappeared with the reconstitution of IOP. The complications such as flat chamber, ciliary body or choroidal detachment were not observed. After the operation, there was an obvious diffuse bleb in all the eyes, and among them., there were 42 eyes with type I diffuse bleb and 6 eyes with type II diffuse bleb. At 6 months postoperatively, there were 32 eyes with type I diffuse bleb, 11 eyes with type II and 1 eye with type III diffuse bleb. CONCLUSION: Nonperforating trabecular surgery with reticulated hyaluronic acid implant can effectively lower the IOP and reduce the sorts of anti-glaucoma medications. The post-operative complications were much less because of no intraoperative penetration of the anterior chamber. Therefore, NPTS is a new, simple and effective way for the treatment of open-angle glaucoma. LA: Chinese
Dr. Y. Guo, Department of Ophthalmology, Xiangya Hospital of Central South University, Changsha 410008 Hunan Province, China
Classification:
12.8.3 Non-perforating (Part of: 12 Surgical treatment > 12.8 Filtering surgery)
