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Abstract #13614 Published in IGR 8-2
Effect of levobunolol switched from timolol gel-forming solution
Inoue K; Wakakura M; Inouye J; Tomita GJapanese Journal of Clinical Ophthalmology 2006; 60: 263-267
PURPOSE: To evaluate ocular hypotensive effect and comfort before and after switching 0.5% timolol gel-forming solution to levobunolol once daily. METHOD: This prospective study involved 35 eyes of 35 glaucoma patients. The series comprised 13 males and 22 females and included primary open-angle glaucoma 24 eyes, normal-tension glaucoma seven eyes, primary angle closed glaucoma three eyes and ocular hypertension one eye. Intraocular pressure (IOP) was measured once a month for three months. RESULTS: IOP before switching averaged 17.1 ± 1.9 mmHg. It decreased significantly two months after switching. There was no difference from baseline value one and three months after switching. Patients complained of stickiness and blurred vision before switching. Levobunolol was preferred to timolol by 18 patients (51%). CONCLUSION: There was not difference in IOP before and after switching timolol to levobunolol up to three months. Ocular comfort was better while using levobunolol than timolol gel-forming solution. LA: Japanese
Dr. K. Inoue, Inouye Eye Hospital, 4-3 Kanda-Surugadai Chiyoda, Tokyo 101-0062, Japan
Classification:
11.3.4 Betablocker (Part of: 11 Medical treatment > 11.3 Adrenergic drugs)