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Abstract #13616 Published in IGR 8-2
Ocular hypotensive effects of adjunctive 1% brinzolamide and 1% dorzolamide for normal-tension glaucoma
Nitta N; Yukawa E; Morishita K; Nawa Y; Hara YJapanese Journal of Clinical Ophthalmology 2006; 60: 193-196
We evaluated the additive effect of 1% brinzolamide and 1% dorzolamide on 34 eyes of 34 cases of normal-tension glaucoma. The patients had been receiving latanoprost or beta-blockers. In 18 eyes that received brinzolamide, the baseline intraocular pressure (TOP) averaged 16.3 ± 2.5 mmHg. IOP decreased significantly 1, 3 and 6 months after addition of brinzolamide. In 16 eyes that received dorzolamide, the baseline IOP averaged 16.1 ± 3.3 mmHg. IOP decreased significantly only 6 months after addition of dorzolamide. Considering the known side effects, 1% brinzolamide is to be preferred to 1% dorzolamide for normal-tension glaucoma. LA: Japanese
Dr. E. Yukawa, Department of Ophthalmology, Nara Medical University, 840 Shijo, Kashihara 634-8521, Japan
Classification:
11.5.2 Topical (Part of: 11 Medical treatment > 11.5 Carbonic anhydrase inhibitors)
