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Abstract #13620 Published in IGR 8-2
The natural history of glaucoma and ocular hypertension after pediatric cataract surgery
Egbert JE; Christiansen SP; Wright MM; Young TL; Summers CGJournal of AAPOS 2006; 10: 54-57
INTRODUCTION: We sought to define the prevalence and natural history of ocular hypertension and glaucoma for at least a ten-year period after pediatric cataract surgery. METHODS: We conducted a prospective observational study of patients who received pediatric cataract surgery. Inclusion criteria included two directed ophthalmologic examinations performed at a minimum of 5 and 10 years after surgery. RESULTS: A total of 63 patients (22 with bilateral cataracts and 41 with unilateral cataracts) were examined at a median of 15.1 year (range, 10.3-21.3 years) after surgery. A majority of the subjects had glaucoma or ocular hypertension (ie, 59%; 37/63). Nineteen percent (12/63) had glaucoma (5/22 with bilateral cataracts and 7/41 with unilateral cataracts). Approximately half (7/12) had developed glaucoma during the first five-year observational period and the remainder (5/12) developed it during the following observational period. Forty percent (25/63) of the patients had ocular hypertension in at least one aphakic eye (9/23 with bilateral cataracts and 16/40 with unilateral cataracts). The rate of progression from ocular hypertension to glaucoma over a mean observational period of 7.2 years (range, 6.2-8.1 years) was 23% (5/22). DISCUSSION: Patients who receive surgery for pediatric cataracts are at very high risk of developing ocular hypertension and glaucoma. Patients can develop late-onset glaucoma and ocular hypertension more than ten years after surgery. Years of ocular hypertension may precede the diagnosis of late-onset glaucoma.
Dr. J.E. Egbert, Department of Surgery, Division of Ophthalmology, 751 South Bascom Avenue, San Jose, CA 95128-2699, USA
Classification:
9.3 Primary angle closure glaucomas (Part of: 9 Clinical forms of glaucomas)
