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Abstract #14189 Published in IGR 8-3
Triamcinolone-induced intraocular pressure elevation: intravitreal injection for macular edema and posterior subtenon injection for uveitis
Sea SY; Byon IS; Oum BSKorean Journal of Ophthalmology 2006; 20: 99-103
PURPOSE: To assess the effect of intravitreal and posterior subtenon injections of triamcinolone acetonide (TA) on intraocular pressure (IOP). METHODS: we reviewed 42 consecutive eyes after intravitreal TA injection (IVTA) and 43 eyes following posterior subtenon TA injection (PSTA). All cases had a minimum follow-up time of three months. After injection, the value and time of the maximal IOP, the amount of IOP elevation and the needs of the medication were assessed. RESULTS: The lOP increased significantly (p < 0.001) from 16.3 ± 2.5 mmHg preoperatively to a mean maximum of 21.7 ± 5.3 mmHg in the IVTA group, and from 15.3 ± 4.5 mmHg to 20.6 ± 3.0 mmHg in the PSTA group. An elevation in the IOP of more than 5 mmHg from the baseline lOP was seen in 52.4% of the IVTA group at a mean time of 3.1 weeks postoperatively, and 44.2% of the PSTA group displayed an IOP elevation at 5.9 weeks. CONCLUSIONS: Both developed significant elevations of IOP, but this appeared at a later date in the PSTA group. Careful follow-up after local injection of steroids is necessary.
Dr. S.Y. Sea, Department of Ophthalmology, College of Medicine, Pusan National University, Busan, Korea. jeasy@hanmail.net
Classification:
9.4.1 Steroid-induced glaucoma (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders)