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Abstract #14244 Published in IGR 8-3
T cell subset expression in the peripheral blood of angle-closure glaucoma patients
Zhu B-Y; Wang W-N; Pan X-FInternational Journal of Ophthalmology 2006; 6: 618-619
AIM: To understand the whole immunologic balance state of the body of angle-closure glaucoma (ACG) patient by testing T cell subset in the peripheral blood of ACG patient with monoclonal antibody technique. METHODS: T cell subsets in the peripheral blood of 45 ACG patients were tested with alkaline phosphatase-antialkaline phosphatase (APAAP) method of monoclonal antibody technique and analyzed with matched control. RESULTS: The percentage of CD3+ cells of ACG group was low er than that of control group (P < 0.005), the percentages of CD4+ cells and CD8+ cells of ACG group were higher than those of control group (P < 0.01 and P < 0.001) and the CD4+/CD8+ ratio of ACG group was lower than that of control group (P < 0.001). CONCLUSION: Autoimmuno-regulatory dysfunction exists in the body of ACG patient and may be one of the factors initiating the occurrence of the disease. LA: Chinese
Dr. B.-Y. Zhu, Department of Ophthalmology, Tangdu Hospital, Fourth Military Medical University, Xi'an 710038 Shaanxi Province, China
Classification:
9.3.1 Acute primary angle closure glaucoma (pupillary block) (Part of: 9 Clinical forms of glaucomas > 9.3 Primary angle closure glaucomas)
