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Abstract #14251 Published in IGR 8-3
The injury mechanism of the primary glaucoma's optic nerve
Fan J-H; Jiang HInternational Journal of Ophthalmology 2006; 6: 428-432
At present there are various pathogeneses on primary glaucoma, but none can explain the injury mechanism of primary glaucoma's optic nerve. After integrated analyses, we discover that both normal people and glaucoma patients have factors indudng injury or resisting injury to optic nerve, and that the glaucoma happen or not depending on the result of the contend between the two factors. Intraocular pressure (IOP) is not only the factor that induces injury of the optic nerve, but also the major risk factor of glaucoma. On the other hand, blood circulation and immunity are also important causes leading to injury of optic nerve. This article analyzed the recent researches on the injury mechanism of the primary glaucoma's optic nerve and the concrete mechanism of IOP inducing glaucoma optic nerve injury from a distinct persective. LA: Chinese
Dr. J.-H. Fan, Department of Ophthalmology, Jinan Clinical Hospital, Second Military Medical University, Jinan 250031 Shandong Province, China
Classification:
1.3 Pathogenesis (Part of: 1 General aspects)