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Abstract #14305 Published in IGR 8-3
Multifocal visual evoked potential in the detection of glaucomatous field defects
Sun C-B; Chen X-MOphthalmology in China 2006; 15: 122-126
OBJECTIVE: To evaluate the effect of multifocal visual evoked potential (mfVEP)on the detection of glaucomatous field defects. DESIGN: Case-controlled study. PARTICIPANTS: Twenty healthy individuals and 20 patients with primary glaucoma accepted mfVEP test. METHODS: Twenty healthy individuals and 20 patients with primary glaucoma were tested with RETIscan multifocal VEP System 3.20 and OCTOPUS 101 automated perimetry G2 test program. Amplitudes were measured and interocular response asymmetry coefficient (RAC) was calculated for each site from all participants. The abnormal areas from mfVEP test were compared with field defects from automated perimetry. MAIN OUTCOME MEASURES: Amplitude, RAC. RESULTS: Ninety percent of suffered eyes showed at least 3 adjacent points had an amplitude decrease or RAC outside 2 standard deviations (SD) from healthy individual database, in which 63% showed at least 3 adjacent points had an amplitude decrease outside 2 SD from normal database while 70% showed at least 3 adjacent points had a RAC outside 2 SD from normal database. 2 patients (2 eyes) had field defects in mfVEP though automated perimetry showed normal field. None of the healthy showd field defects in mfVEP test. CONCLUSIONS: mfVEP could be used to detect field defects of glaucoma. LA: Chinese
Dr. C.-B. Sun, Eye Hospital, Wenzhou Medical College, Wenzhou 325003, China
Classification:
6.7 Electro-ophthalmodiagnosis (Part of: 6 Clinical examination methods)
