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Abstract #14309 Published in IGR 8-3

Evaluation of the therapeutic effects of trabeculectomy combined with Schlemm canal suture implantation in primary open-angle glaucoma

Pan W-H; Li C; Wang W-B; Zhang Y-J
Ophthalmology in China 2006; 15: 108-111


OBJECTIVE: To evaluate the therapeutic effects and safety of trabeculectomy combined with Schlemm canal suture implantation in patients POAG). DESIGN: Retrospective, noncomparative case series. PARTICIPANTS: 11 patients (19 eyes) with POAG. METHODS: Two layers of scleral flap were made and the deeper one was dissected. The outer wall of Schlemm canal was cut away. 6-0 nylon thread was implanted between the two cut ends of the canal. Penetrating trabeculectomy was performed and followed with peripheral iridectomy. Superficial scleral flap was sutured. Main outcome measures: The postoperative observation included intraocular pressure (IOP), formation of the anterior chamber, inflammatory reaction, visual acuity, complications and situation of filtering bleb. RESULTS: The mean postoperative follow-up period was 18.05 ± 12.78 months (ranging from 6 to 48 months). There was significant statistical difference between preoperative and postoperative IOPs (31.23 ± 9.72 mmHg VS 15.11 ± 6.13 mmHg) (t = 6.769, P = 0.000). The post-operative investigation of IOP for 11 cases (19 eyes) after using medicine showed that IOP 22 mmHg only 1 case. The efficiency was 94.74%. Filtering blebs formed in 6 cases (8 eyes) (42.11%), including the case with IOP 22 mmHg. There was no significant difference in change of preoperative and postoperative IOP in patients with or without filtering blebs with t-test (t = -1.662, P = 0.071). The anterior chamber formed well in each case postoperatively. Hyphemia appeared in 4 eyes (21.05%). Hypertonia oculi (IOP > 22 mmHg) and hypotonia oculi (IOP ≤ 6 mmHg) appeared occasionally in 3 eyes (15.78%) and 11 eyes (57.89%) respectively. Postoperatively, no fibrinous exudates in anterior chamber, choroidal detachment and other complications occurred in any case. CONCLUSIONS: The control of IOP appears to be good after the surgery of trabeculectomy combined with Schlemm canal suture implantation. It is a promising approach for glaucoma and good with fewer postoperative complications, easier postoperative management and deserve further development. LA: Chinese

Dr. W.-H. Pan, Department of Ophthalmology, Hospital of Ningxia Medical College, Yinchuan 750001, China


Classification:

12.8.1 Without tube implant (Part of: 12 Surgical treatment > 12.8 Filtering surgery)



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