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OBJECTIVE: To evaluate the efficacy and safety of non-penetrating trabecular surgery (NPTS) with T-Flux implant in primary open-angle glaucoma (POAG). DESIGN: Retrospective case series study. PARTICIPANTS: Eighty-five patients (107 eyes) with POAG. METHODS: 85 primary open-angle glaucoma patients (107 eyes) underwent NPTS with T-Flux implant. The average follow-up period was 12 to 24 months (mean follow-up time was 18.7 ± 5.0 months). The visual acuity, intraocular pressures (IOP), cup/disc ratio, filtering blebs, and the complications were observed. Main outcome measures: Visual acuity, intraocular pressures(IOP), cup/disc ratio, filtering blebs, anterior chamber depth, operative and postoperative complications. RESULTS: The preoperative IOP from a mean value of 31.5 ± 7.8 mmHg decreased postoperatively to 17.9 ± 4.2 mmHg at 1 year, 17.8 ± 4.2 mmHg at 1.5 years, and 18.9 ± 5.1 mmHg at 2 years (P < 0.001). The rate of complete success (IOP≤ 21 mmHg without medication) was 86.9% at 1 year, 83.6% at 1.5 years, and 79.6% at 2 years. The rate of partial success (IOP≤ 21 mmHg with topical medication) was 88.9% at 1 year, 86.5% at 1.5 years, and 81.5% at 2 years. The success rate was significantly depending on formation and retention of the reflective filtering bleb, but not on perforation of the trabeculo-Descemet membrane. The peri-operative complications were perforation of the trabeculo-Descemet membrane and hyphema. The early postoperative complications were ocular hypotony, flat anterior chamber, and choroidal detachment. CONCLUSION: NPTS with T-Flux implant is a safe operation which can provide reasonable control of IOP in POAG. LA: Chinese
Dr. W.-Y. Guo, Department of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai 200031, China
12.8.2 With tube implant or other drainage devices (Part of: 12 Surgical treatment > 12.8 Filtering surgery)
12.8.3 Non-perforating (Part of: 12 Surgical treatment > 12.8 Filtering surgery)