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Abstract #14656 Published in IGR 8-4
Effect of monotherapy with nipradilol ophthalmic solution for normal-tension glaucoma
Yukawa E; Nitta N; Taketani F; Yoshii T; Matsuura T; Morishita K; Hara YJapanese Journal of Clinical Ophthalmology 2006; 60: 1685-1689
PURPOSE: To report the effect of nipradilol ophthalmic solution for normal-tension glaucoma. Cases and METHOD: This prospective study was performed on 46 eyes of 46 patients who were diagnosed with normal-tension glaucoma in three institutions. The series comprised 18 males and 28 females. Their age ranged from 35 to 83 years, average 65 years. They were treated by topical nipradilol alone. Intraocular pressure (IOP) was measured every 6 months. Visual field was evaluated by program 30-2 of Humphrey perimeter. Deterioration by more than 3 dB was regarded as progression. Baseline IOP averaged 15.7 mmHg. RESULTS: IOP decreased significantly until 36 months after start of treatment. When judged by life table of Kaplan-Meier, the visual field showed 4-year survival of 83.2%. CONCLUSION: Monotherapy with topical nipradilol is effective for IOP reduction and prevention of progression of visual field defect in normal-tension glaucoma. LA: Japanese
Dr. E. Yukawa, Department of Ophthalmology, Nara Medical University, 840 Shijo-cho, Kashihara 634-8522, Japan
Classification:
9.2.4 Normal pressure glaucoma (Part of: 9 Clinical forms of glaucomas > 9.2 Primary open angle glaucomas)
11.3.5 Other (Part of: 11 Medical treatment > 11.3 Adrenergic drugs)
