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Abstract #14826 Published in IGR 8-4
The long term curative effect of the nonpenetrating trabecular surgery
Huang Y; Wang N-L; Wang B-W; Li L-JOphthalmology in China 2006; 15: 277-280
OBJECTIVE: To evaluate the long term curative effectiveness and the failure cause of the nonpenetrating trabecular surgery (NPTS) for primary open angle glaucoma (POAG). DESIGN: Randomized clinical trial. PARTICIPANTS: One hundred and five patients (111 eyes) with POAG. METHODS: Fifty-two patients (55 eyes) and 53 patients (56 eyes) underwent NPTS and trabeculectomy respectively. The follow-up period was 30 to 48 months (mean, 40.1±8.2 months). MAIN OUTCOME MEASURES: Visual acuity, intraocular pressure (IOP), filtering blebs, alteration of anterior chamber angle and complications. RESULTS: Visual acuity in the NPTS group was significantly superior to that in the trabeculectomy group (Χ2 = 7.7381, P < 0.05). The successful rate at 6,12,24,36,48 months after operation was 91%, 77%, 70%, 67%, 60% in the NPTS group and 90%, 86%, 82%, 81%, 78% in the trabecalectomy group. There was no significant difference between the two groups at 6, 12, 24, 36 months after operation Χ2 =0.08, 0.748, 2.93, 3.53; P > 0.05, respectively). But the successful rate in the NPTS group 48 months after operation was significantly lower than that in the trabecalectomy group (Χ2 = 5.26, P < 0.05). Only 47% of functional filtering blebs were preserved in NPTS group 48 months after operation, which was lower than that in the trabecalectomy group (76%). The filtration membrane at the operation area of 30 cases (54.5%) in the NPTS group was fibrously thickened and peripheral anterior synechia was found in 12 cases (21.8%). CONCLUSIONS: The success rate of the NPTS is equal to trabeculectomy in short or intermediate term. But it is lower in long term of 48 months. The increase of IOP after the NPTS is related to the fibrous thickening of the filtration membrane in the operation area and the peripheral anterior synechia. LA: Chinese
Dr. Y. Huang, Department of Ophthalmology, Hospital of Guangdong Medical College, Zhangjiang 524003, China
Classification:
12.8.3 Non-perforating (Part of: 12 Surgical treatment > 12.8 Filtering surgery)
12.8 Filtering surgery (Part of: 12 Surgical treatment)
