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Abstract #14915 Published in IGR 8-4
Sector-based analysis of the distribution of the neuroretinal rim by confocal scanning laser in the diagnosis of glaucoma
Pueyo V; Larrosa JM; Polo V; Perez Inigo A; Ferreras A; Honrubia FMArchivos de la Sociedad Española de Oftalmologia 2006; 81: 135-140
PURPOSE: To evaluate the diagnostic ability of the Moorfields regression analysis (MRA; neuroretinal rim sector-based analysis) by means of confocal scanning laser. METHODS: two hundred eyes were included in this study: 101 normal subjects and 99 glaucoma patients (standard automated perimetry with glaucomatous defects -MD or CPSD with p < 0.02 or a cluster of three or more points with p < 0.05 or a cluster of two or more points with p < 0.01 or abnormal Glaucoma Hemifield Test). All subjects underwent a full ophthalmic evaluation, visual field evaluation by means of a Humphrey Field Analyzer, 24-2 full threshold strategy, and optic disc topography by Heidelberg retina tomograph (HRT-II). The outcome parameters were sensitivity and specificity of the MRA for each sector. RESULTS: The highest sensitivity in detecting structural defects based on MRA (p < 0.05) was observed in the nasal-superior sector (48%) and nasal-inferior sector (45%); however the highest specificity was found in the temporal-superior (98%) and inferior (98%) sectors. The highest sensitivity for MRA (p < 0.01) was found in the temporal-inferior sector (31%) and nasal-superior sector (30%) while the temporal-superior and inferior-sectors showed the highest specificity (100%). The diagnosis of glaucoma based on the presence of any sector alteration showed sensitivity figures of 67% with p < 0.05 and 46% with p < 0.01 and specificity values of 84% with p < 0.05 and 96% with p < 0.01. CONCLUSIONS: The analysis of the distribution of the neuroretinal rim by means of HRT-II contributes effectively to the diagnosis of glaucoma based on perimetry in a sample derived from a Spanish population. LA: Spanish
Dr. V. Pueyo, Servicio de Oftalmologia, Hospital Universitario Miguel Servet, Zaragoza, Spain. vicpueyo@hotmail.com
Classification:
6.9.1 Laser scanning (Part of: 6 Clinical examination methods > 6.9 Computerized image analysis)
6.6.2 Automated (Part of: 6 Clinical examination methods > 6.6 Visual field examination and other visual function tests)
