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Abstract #15503 Published in IGR 1-3
A case of drug-induced limbal dysfunction due to antiglaucoma eyedrops
Noda K; Konishi M; Yamada M; Tanino T; Mashima YFolia Ophthalmologica Japonica / Nihon Ganka Kiyo 1999; 50: 667-670
The authors report a case of limbal dysfunction caused by long-term instillation of antiglaucoma drugs. The patient was a 69-year-old male who had undergone cataract surgery in the right eye. When intraocular pressure became elevated postoperatively, 0.5% timolol maleate and 0.1% dipivefrin hydrochloride were started. After 3.5 years of treatment, a persistent epithelial defect with limbal dysfunction developed that was thought to be due to the long-term use of antiglaucoma medications. The epithelial defect was successfully treated by keratoepithelioplasty (KEP), but intraocular pressure became elevated postoperatively due to corticosteroid use after KEP. Trabeculotomy was performed and intraocular pressure was well-controlled after this operation. In cases of steroid-induced glaucoma associated with drug-induced limbal dysfunction, treatment is difficult because the ocular surface must be restored while intraocular pressure is controlled. Attention must be paid to early changes in the ocular surface when antiglaucoma agents are used.LA: Japanese
Dr. K. Noda, Department of Ophthalmology, National Tokyo Medical Center, 2-5-1 Higashigaoka, Meguro-ku, Tokyo 152-8902; Japan
Classification:
11.3.1 Epinephrine (Part of: 11 Medical treatment > 11.3 Adrenergic drugs)
11.3.4 Betablocker (Part of: 11 Medical treatment > 11.3 Adrenergic drugs)
