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Abstract #15589 Published in IGR 1-3
A major review of antimetabolites in glaucoma therapy
Loon SC; Chew PTKOphthalmologica 1999; 213: 234-245
Antimetabolites have been used in combination with filtering surgery to improve surgical results for more than ten years. Based on research published since the introduction of antimetabolites right up to date, the authors discuss the various forms of antimetabolites that have been used, including drugs and irradiation. Among the drugs used, mitomycin C and 5-fluorouracil are the most prominent. They discuss the background of these agents, the progress in the use of antimetabolites and the research done on these drugs. These agents have been used both intraoperatively and perioperatively. The authors discuss the indications for their use, their mode of action, the techniques of usage, their variations, as well as the complications and the treatment of complications.
Dr. S.C. Loon, Department of Ophthalmology, National University Hospital; Singapore
Classification:
12.8.10 Woundhealing antifibrosis (Part of: 12 Surgical treatment > 12.8 Filtering surgery)
