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PURPOSE: To assess changes in the nerve fiber layer thickness after trabeculectomy using scanning laser polarimetry. METHODS: The authors prospectively enrolled 46 eyes from 46 patients with primary open-angle glaucoma in whom intraocular pressure had been reduced by more than 30% after trabeculectomy without significant ophthalmic complications and from whom good quality images were obtained by a scanning laser polarimetry preoperatively and at three to six months after trabeculectomy. In each enrolled eye, changes in the nerve fiber layer thickness after surgery in the defined ring (1.8 disc diameters) around the optic disc were calculated in 10° intervals (36 sectors in total) and in the following four quadrants (the sum of nine 10° sectors): superior, nasal, inferior, and temporal. RESULTS: The mean intraocular pressure was 22.6 ± 6.9 mmHg preoperatively and 10.2 ± 3.7 mmHg postoperatively (p < 0.01). According to the analyses at every 10°, the postoperative nerve fiber layer thickness was significantly greater than the preoperative nerve fiber layer thickness in the superotemporal region (10-50 Dr. N. Hamada, Department of Ophthalmology, Gifu University School of Medicine, Japan 2.13 Retina and retinal nerve fibre layer (Part of: 2 Anatomical structures in glaucoma)Classification:
6.9.1 Laser scanning (Part of: 6 Clinical examination methods > 6.9 Computerized image analysis)
12.8.10 Woundhealing antifibrosis (Part of: 12 Surgical treatment > 12.8 Filtering surgery)